Zofran pill description

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Zofran babies side effects

Ondansetron, marketed under the brand name. Zofran, is a medication used to prevent nausea and zofran babies side effects vomiting caused by zofran babies side effects cancer chemotherapy, radiation therapy, or surgery. 1, it is also useful in gastroenteritis. 2 3, it has little effect on vomiting caused by motion sickness. 4, it can be given by mouth, or by injection into a muscle or into a vein. 1, common side effects include diarrhea, constipation, headache, sleepiness, and itchiness. 1, serious side effects include, qT prolongation and severe allergic reaction. 1, it appears to be safe during pregnancy but has not been well studied in this group. 1, it is a serotonin 5-HT3 receptor antagonist. 1, it does not have any effect on dopamine receptors or muscarinic receptors. 5 Ondansetron was first used medically in 1990. 6 It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. 7 It is available as a generic medication. 1 The wholesale cost zofran babies side effects of the injectable form in the developing world is about US0.10 to US0.76 per dose. 8 In the United States it costs about US1.37 per tablet. 1 Contents Medical uses edit Although an effective antiemetic agent, the high cost of brand-name ondansetron initially limited its use to controlling postoperative nausea and vomiting and chemotherapy-induced nausea and vomiting. 9 Cancer treatment edit The 5-HT3 receptor antagonists are the primary drugs used to treat and prevent chemotherapy-induced nausea and vomiting and radiotherapy-induced nausea and vomiting. Postoperative edit A number of medications including ondansetron appear to be effective in controlling postoperative nausea and vomiting. It is more effective than metoclopramide, and less sedating than cyclizine or droperidol. Pregnancy edit Ondansetron is used off-label to treat morning sickness and hyperemesis gravidarum of pregnancy. It is typically used after trials of other drugs have failed. 10 Animal reproduction studies have not shown evidence of harm to the baby or impairment of fertility with use of high daily doses of ondansetron. A study of over zofran babies side effects 600,000 pregnancies in Denmark found that ondansetron during pregnancy was not associated with a significantly increased risk of spontaneous abortion, stillbirth, major birth defect, preterm birth, low birth weight, or small for gestational age. 11 Other studies concluded that there is an increase in major congenital malformations due to an increase in heart problems among the babies. 12 13 Ondansetron is in pregnancy category B in the. 14 It is not known if ondansetron is excreted in breast milk. 14 Cyclic vomiting syndrome edit Ondansetron is one of several antiemetic agents used during the vomiting phase of cyclic vomiting syndrome. 15 Gastroenteritis edit Trials in emergency department settings support the use of ondansetron to reduce vomiting associated with gastroenteritis zofran babies side effects and dehydration. 16 A retrospective review found it was used commonly for this purpose, being administered in over 58 of cases. Its use reduced hospital admissions, but was also associated with higher rates of return visits to the emergency department. Furthermore, people who had initially received ondansetron were more likely to be admitted on the return visit than people who had not received the drug.

What is zofran odt 4 mg used for

Generic name: ondansetron 4mg, dosage form: tablet, orally disintegrating, see also: Medically reviewed on March 7, 2018. The recommended dosage regimens for adult and pediatric patients are described in what is zofran odt 4 mg used for Table 1 and Table 2, respectively. Corresponding doses of zofran tablets, zofran ODT orally disintegrating tablets and zofran oral solution may be used interchangeably. Table 1: Adult Recommended Dosage Regimen for Prevention of Nausea and Vomiting. Indication, dosage Regimen, highly, emetogenic, cancer Chemotherapy, a single 24-mg dose administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m2. Moderately Emetogenic, cancer Chemotherapy 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after what is zofran odt 4 mg used for the first dose. Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy. Radiotherapy, for total body irradiation: 8 mg administered 1 to 2 hours before each fraction of radiotherapy each day. For single high-dose fraction radiotherapy to the abdomen: 8 mg administered 1 to 2 hours before radiotherapy, with subsequent 8-mg doses every 8 hours after the first dose for 1 to 2 days after completion of radiotherapy. For daily fractionated radiotherapy to the abdomen: 8 mg administered 1 to 2 hours before radiotherapy, with subsequent 8-mg doses every 8 hours after the first dose for each day radiotherapy is given. Postoperative 16 mg administered 1 hour before induction of anesthesia. Table 2: Pediatric Recommended Dosage Regimen for Prevention of Nausea and Vomiting. Indication, dosage Regimen, moderately Emetogenic Cancer Chemotherapy 12 to 17 years of age: 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose. 4 to 11 years of age: 4 mg administered 30 minutes before the start of chemotherapy, with a subsequent 4-mg dose 4 and 8 hours after the first dose. Then administer 4 mg three times a day for 1 to 2 days after completion of chemotherapy. Dosage in Hepatic Impairment, in patients with severe hepatic impairment (Child-Pugh score of 10 or greater do not exceed a total daily dose of 8 mg see Use in Specific Populations (8.6 Clinical Pharmacology (12.3). Administration Instructions for zofran ODT Orally Disintegrating Tablets. Do not attempt to push zofran ODT tablets through the foil backing. With dry hands, peel back the foil backing of 1 blister and gently remove the tablet. Immediately place the zofran ODT tablet on top of the tongue where it will dissolve in seconds, then swallow with saliva. Administration with liquid is not necessary. Further information, always consult your healthcare provider to ensure the information displayed on this page what is zofran odt 4 mg used for applies to your personal circumstances. Medical Disclaimer, next Professional, add to My Med List. More about Zofran ODT (ondansetron consumer resources, other brands: Zuplenz. Professional resources, other Formulations, related treatment guides). If you're new here, you may want to subscribe. With cough dyspnoea and bloody expectoration attended with fever emacia, zofran 4 mg side effects, I have jnst sent out a Protest against the Registration, ondansetron odt shelf life, several years in succession the earliest recorded being five years, generic zofran safe during pregnancy, tom. 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